{"id":14951,"date":"2022-07-26T11:01:31","date_gmt":"2022-07-26T09:01:31","guid":{"rendered":"https:\/\/havas.cz\/?post_type=pressroom&p=14951"},"modified":"2022-07-26T11:01:32","modified_gmt":"2022-07-26T09:01:32","slug":"prumerna-doba-diagnozy-bechterevovy-nemoci-je-devet-let-lide-si-ji-casto-pletou-s-beznou-bolesti-zad","status":"publish","type":"pressroom","link":"https:\/\/havas.cz\/en\/pressroom\/prumerna-doba-diagnozy-bechterevovy-nemoci-je-devet-let-lide-si-ji-casto-pletou-s-beznou-bolesti-zad\/","title":{"rendered":"Pr\u016fm\u011brn\u00e1 doba diagn\u00f3zy Becht\u011brevovy nemoci je dev\u011bt let. Lid\u00e9 si ji \u010dasto pletou s b\u011b\u017enou bolest\u00ed zad"},"content":{"rendered":"\n

Ankylozuj\u00edc\u00ed spondylitida. Toto t\u011b\u017eko zapamatovateln\u00e9 spojen\u00ed pojmenov\u00e1v\u00e1 nevyl\u00e9\u010diteln\u00e9 z\u00e1n\u011btliv\u00e9 revmatick\u00e9 onemocn\u011bn\u00ed zvan\u00e9 tak\u00e9 Becht\u011brevova choroba. P\u0159\u00ed\u010dina nemoci nen\u00ed zcela jasn\u00e1. Pravd\u011bpodobn\u011b se na n\u00ed ale pod\u00edl\u00ed kombinace genetick\u00e9 predispozice s faktory vn\u011bj\u0161\u00edho prost\u0159ed\u00ed, kter\u00e9 aktivuj\u00ed imunitn\u00ed syst\u00e9m. V \u010cesk\u00e9 republice trp\u00ed t\u00edmto autoimunitn\u00edm onemocn\u011bn\u00edm asi deset tis\u00edc pacient\u016f. V posledn\u00edch letech v\u0161ak jejich po\u010det nar\u016fst\u00e1 hlavn\u011b kv\u016fli v\u011bt\u0161\u00edmu pov\u011bdom\u00ed o nemoci a lep\u0161\u00ed diagnostice. Becht\u011brevova nemoc se vyskytuje t\u0159ikr\u00e1t \u010dast\u011bji u mu\u017e\u016f ne\u017e u \u017een a prvn\u00ed p\u0159\u00edznaky se objevuj\u00ed mezi 18. a 30. rokem \u017eivota.2<\/sup><\/p>\n\n\n\n

Projevy onemocn\u011bn\u00ed<\/strong><\/p>\n\n\n\n

Mezi hlavn\u00ed varovn\u00e9 sign\u00e1ly pat\u0159\u00ed bolest v doln\u00ed \u010d\u00e1sti zad spole\u010dn\u011b se ztuhlost\u00ed, kter\u00e1 trv\u00e1 d\u00e9le ne\u017e t\u0159i m\u011bs\u00edce. Lid\u00e9 ji v\u0161ak \u010dasto zam\u011b\u0148uj\u00ed za klasickou bolest zad. Dal\u0161\u00edm sign\u00e1lem b\u00fdv\u00e1 bolest v oblasti hrudn\u00edku a omezen\u00ed rozsahu pohybu p\u00e1te\u0159e, odkud prostupuje do h\u00fd\u017ed\u00ed a zadn\u00ed strany stehen. Polovina pacient\u016f m\u00e1 z\u00e1n\u011btem zasa\u017een\u00e9 tak\u00e9 klouby a \u00fapony mimo p\u00e1te\u0159. Bolest a omezen\u00e1 hybnost se typicky objevuje v klidu v noci a po r\u00e1nu.2<\/sup> \u201eUb\u00edjej\u00edc\u00ed je ohromn\u00e1 nevypo\u010ditatelnost nemoci. Nikdy nev\u00edte, kdy se vzbud\u00edte s nov\u00fdm z\u00e1n\u011btem kloubu, v\u010detn\u011b \u010delistn\u00edch kloub\u016f,\u201c <\/em>sv\u011b\u0159uje se se sv\u00fdmi zku\u0161enostmi pacient Lud\u011bk. V n\u011bkter\u00fdch p\u0159\u00edpadech se objevuj\u00ed i mimokloubn\u00ed p\u0159\u00edznaky nemoci, kter\u00e9 postihuj\u00ed o\u010di (a\u017e 30 % p\u0159\u00edpad\u016f), k\u016f\u017ei (lup\u00e9nka a\u017e ve 20 % p\u0159\u00edpad\u016f) \u010di st\u0159eva (5\u201310 %).3<\/sup><\/p>\n\n\n\n

Diagnostika Becht\u011brevovy nemoci<\/strong><\/p>\n\n\n\n

P\u0159i diagnostice nemoci se p\u0159ihl\u00ed\u017e\u00ed i k rentgenov\u00fdm sn\u00edmk\u016fm a krevn\u00edm test\u016fm. Bohu\u017eel ale n\u011bkter\u00e9 \u010dasn\u00e9 formy onemocn\u011bn\u00ed nejsou na rentgenu rozpoznateln\u00e9, a p\u0159esn\u00e1 diagn\u00f3za se tak oddaluje. Pr\u016fm\u011brn\u00e1 doba od prvn\u00edch p\u0159\u00edznak\u016f po stanoven\u00ed kone\u010dn\u00e9 diagn\u00f3zy je u n\u00e1s 9,1 roku.1<\/sup> \u010c\u00edm d\u0159\u00edve se v\u0161ak p\u0159ijde na p\u0159\u00ed\u010dinu nemoci, t\u00edm d\u0159\u00edve pacient dostane vhodnou l\u00e9\u010dbu a m\u016f\u017ee se zabr\u00e1nit dal\u0161\u00edmu rozvoji choroby. Pokud se s l\u00e9\u010dbou za\u010dne pozd\u011b, p\u0159\u00edpadn\u00e9 zm\u011bny na p\u00e1te\u0159i a kloubech jsou ji\u017e nevratn\u00e9.4<\/sup><\/p>\n\n\n\n

Mo\u017enosti l\u00e9\u010dby<\/strong><\/p>\n\n\n\n

Existuj\u00ed farmakologick\u00e9 a nefarmakologick\u00e9 mo\u017enosti l\u00e9\u010dby Becht\u011brevovy nemoci v z\u00e1vislosti na stadiu onemocn\u011bn\u00ed. Mezi nefarmakologick\u00e9 pat\u0159\u00ed \u00faprava \u017eivotn\u00edho stylu, fyzioterapie, p\u0159\u00edpadn\u011b l\u00e1zn\u011b. \u00dalevu od bolesti a ztuhlosti toti\u017e p\u0159in\u00e1\u0161\u00ed rozh\u00fdb\u00e1n\u00ed kloub\u016f. Farmakologick\u00e1 l\u00e9\u010dba pak zahrnuje v prvn\u00ed \u0159ad\u011b u\u017e\u00edv\u00e1n\u00ed nesteroidn\u00edch antirevmatik (NSA), kter\u00e1 p\u016fsob\u00ed na zm\u00edrn\u011bn\u00ed z\u00e1n\u011btu, bolesti a otok\u016f v posti\u017een\u00fdch m\u00edstech.2<\/sup>Mezi dal\u0161\u00ed l\u00e9\u010diva pat\u0159\u00ed tak\u00e9 kortikoidy a imunosupresiva.6<\/sup><\/p>\n\n\n\n

\u201eV\u011bt\u0161ina pacient\u016f na\u0161t\u011bst\u00ed funguje pom\u011brn\u011b dob\u0159e na prost\u00e9m cvi\u010den\u00ed, rehabilitaci a ob\u010dasn\u00e9m u\u017eit\u00ed nesteroidn\u00edch antirevmatik proti z\u00e1n\u011btu a bolesti. D\u016fle\u017eit\u00e9 je potla\u010den\u00ed autonomn\u00ed reakce v t\u011ble pacienta. Nel\u00e9\u010den\u00e9 onemocn\u011bn\u00ed vede k postupn\u00e9 invalidit\u011b, zhor\u0161ov\u00e1n\u00ed kvality \u017eivota a ve sv\u00e9 podstat\u011b i zkr\u00e1cen\u00ed \u017eivota,\u201c <\/em>p\u0159ibli\u017euje <\/em>prof. MUDr. Ladislav \u0160enolt, Ph.D., vedouc\u00ed odd\u011blen\u00ed experiment\u00e1ln\u00ed revmatologie Revmatologick\u00e9ho \u00fastavu.<\/p>\n\n\n\n

Biologick\u00e1 l\u00e9\u010dba<\/strong><\/p>\n\n\n\n

Dal\u0161\u00ed skupinu l\u00e9k\u016f tvo\u0159\u00ed biologick\u00e1 l\u00e9\u010diva, kter\u00e1 jsou velmi \u00fa\u010dinn\u00e1 a krom\u011b toho, \u017ee p\u016fsob\u00ed na bolest, tak\u00e9 tlum\u00ed z\u00e1n\u011bt kloub\u016f i \u0161lach. D\u00e1le sni\u017euj\u00ed mno\u017estv\u00ed o\u010dn\u00edch komplikac\u00ed, m\u00edrn\u00ed lup\u00e9nku nebo st\u0159evn\u00ed z\u00e1n\u011bt, pokud se tyto komplikace u nemoci vyskytuj\u00ed. Biologick\u00e1 l\u00e9\u010dba je ale ur\u010den\u00e1 pouze t\u011bm pacient\u016fm, kte\u0159\u00ed spl\u0148uj\u00ed podm\u00ednky pro jej\u00ed pod\u00e1n\u00ed.5<\/sup> Jedn\u00edm z krit\u00e9ri\u00ed je nap\u0159\u00edklad selh\u00e1n\u00ed kombinace nefarmakologick\u00e9 l\u00e9\u010dby s u\u017e\u00edv\u00e1n\u00edm nesteroidn\u00edch antirevmatik. Nasazen\u00ed biologick\u00e9 l\u00e9\u010dby v\u017edy z\u00e1vis\u00ed na individu\u00e1ln\u00ed pot\u0159eb\u011b pacienta a doporu\u010den\u00ed l\u00e9ka\u0159e.<\/p>\n\n\n\n

\u201eZp\u016fsob\u016f, jak nemoc pozitivn\u011b ovlivnit a p\u0159edej\u00edt v\u00e1\u017en\u00fdm zdravotn\u00edm komplikac\u00edm, m\u00e1me dnes hned n\u011bkolik. Je ale pot\u0159eba v\u010dasn\u00e9 diagnostiky a aktivn\u00edho p\u0159\u00edstupu pacienta. Pohybem a cvi\u010den\u00edm m\u016f\u017ee pomoci t\u011blu proti bolesti a ztuhlosti a z\u00e1rove\u0148 ho udr\u017e\u00ed v co nejlep\u0161\u00ed kondici. D\u016fle\u017eit\u00e9 je tak\u00e9, aby pacienti informovali sv\u00e9 bl\u00edzk\u00e9 a neb\u00e1li se \u0159\u00edct si o pomoc<\/em>,\u201c uzav\u00edr\u00e1 prof. Ladislav \u0160enolt.<\/p>\n\n\n\n

Kontakt pro m\u00e9dia: <\/strong><\/p>\n\n\n\n

Michaela Jura\u010d\u00e1kov\u00e1, PR Manager, 602 766 398, michaela.juracakova@havaspr.com<\/a><\/p>\n\n\n\n

Zdroje:<\/strong><\/p>\n\n\n\n

  1. FOREJTOVA, S., et al. (2008). Factors influencing health status and disability of patients with ankylosing spondylitis in the Czech Republic. Clin Rheumatol<\/em>. 27(8): 1005\u20131013.<\/li>
  2. Becht\u011brevova nemoc<\/em> [online]. Dostupn\u00e9 z: https:\/\/www.bechterevovanemoc.cz\/<\/a><\/li>
  3. KHAN, MA. Ann Intern Med.<\/em> 2002; 136: 896\u2013907.<\/li>
  4. TAN, S., WANG, R., WARD, M. M.Syndesmophyte growth in ankylosing spondylitis. Curr Opin Rheumatol<\/em>. 2015; 27 (4): 326\u2013332.<\/li>
  5. Ann Rheum Dis doi: 10.1136\/annrheumdis-2016-210770 <\/li>
  6. ZOCHLING, J., et al. Ann Rheum Dis<\/em>. 2006; 65: 442\u2013452<\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"

    Becht\u011brevova nemoc je nen\u00e1padn\u00e1, nevypo\u010ditateln\u00e1 a z\u00e1ke\u0159n\u00e1. Tuhnou p\u0159i n\u00ed klouby a postupem \u010dasu vede k \u00fapln\u00e9mu ztuhnut\u00ed p\u00e1te\u0159e. Lid\u00e9 ji ale \u010dasto zam\u011b\u0148uj\u00ed za b\u011b\u017enou bolest zad a pr\u016fm\u011brn\u011b trv\u00e1 a\u017e dlouh\u00fdch dev\u011bt let, ne\u017e ji l\u00e9ka\u0159i spr\u00e1vn\u011b diagnostikuj\u00ed.1 V\u010dasn\u00e1 diagn\u00f3za a nasazen\u00ed vhodn\u00e9 l\u00e9\u010dby by p\u0159itom mohly zpomalit rozvoj nemoci a pacienti by m\u011bli v\u011bt\u0161\u00ed \u0161anci \u017e\u00edt d\u00e9le plnohodnotn\u011bj\u0161\u00ed \u017eivot. V opa\u010dn\u00e9m p\u0159\u00edpad\u011b se zkracuje \u017eivot pacient\u016f a velk\u00e1 v\u011bt\u0161ina z nich m\u00e1 v\u00fdznamn\u011b omezenou pohyblivost a dal\u0161\u00ed komplikace.2 <\/p>\n","protected":false},"author":48,"featured_media":0,"menu_order":0,"template":"","meta":{"_links_to":"","_links_to_target":""},"pressroom_category":[],"pressroom_tag":[204],"class_list":["post-14951","pressroom","type-pressroom","status-publish","hentry","pressroom_tag-zdravi"],"yoast_head":"\nPr\u016fm\u011brn\u00e1 doba diagn\u00f3zy Becht\u011brevovy nemoci je dev\u011bt let. Lid\u00e9 si ji \u010dasto pletou s b\u011b\u017enou bolest\u00ed zad - Havas Prague<\/title>\n<meta name=\"description\" content=\"Becht\u011brevova nemoc je nen\u00e1padn\u00e1, nevypo\u010ditateln\u00e1 a z\u00e1ke\u0159n\u00e1. Tuhnou p\u0159i n\u00ed klouby a postupem \u010dasu vede k \u00fapln\u00e9mu ztuhnut\u00ed p\u00e1te\u0159e. Lid\u00e9 ji ale \u010dasto zam\u011b\u0148uj\u00ed za b\u011b\u017enou bolest zad a pr\u016fm\u011brn\u011b trv\u00e1 a\u017e dlouh\u00fdch dev\u011bt let, ne\u017e ji l\u00e9ka\u0159i spr\u00e1vn\u011b diagnostikuj\u00ed.1 V\u010dasn\u00e1 diagn\u00f3za a nasazen\u00ed vhodn\u00e9 l\u00e9\u010dby by p\u0159itom mohly zpomalit rozvoj nemoci a pacienti by m\u011bli v\u011bt\u0161\u00ed \u0161anci \u017e\u00edt d\u00e9le plnohodnotn\u011bj\u0161\u00ed \u017eivot. V opa\u010dn\u00e9m p\u0159\u00edpad\u011b se zkracuje \u017eivot pacient\u016f a velk\u00e1 v\u011bt\u0161ina z nich m\u00e1 v\u00fdznamn\u011b omezenou pohyblivost a dal\u0161\u00ed komplikace.2\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/havas.cz\/pressroom\/prumerna-doba-diagnozy-bechterevovy-nemoci-je-devet-let-lide-si-ji-casto-pletou-s-beznou-bolesti-zad\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pr\u016fm\u011brn\u00e1 doba diagn\u00f3zy Becht\u011brevovy nemoci je dev\u011bt let. Lid\u00e9 si ji \u010dasto pletou s b\u011b\u017enou bolest\u00ed zad - Havas Prague\" \/>\n<meta property=\"og:description\" content=\"Becht\u011brevova nemoc je nen\u00e1padn\u00e1, nevypo\u010ditateln\u00e1 a z\u00e1ke\u0159n\u00e1. Tuhnou p\u0159i n\u00ed klouby a postupem \u010dasu vede k \u00fapln\u00e9mu ztuhnut\u00ed p\u00e1te\u0159e. Lid\u00e9 ji ale \u010dasto zam\u011b\u0148uj\u00ed za b\u011b\u017enou bolest zad a pr\u016fm\u011brn\u011b trv\u00e1 a\u017e dlouh\u00fdch dev\u011bt let, ne\u017e ji l\u00e9ka\u0159i spr\u00e1vn\u011b diagnostikuj\u00ed.1 V\u010dasn\u00e1 diagn\u00f3za a nasazen\u00ed vhodn\u00e9 l\u00e9\u010dby by p\u0159itom mohly zpomalit rozvoj nemoci a pacienti by m\u011bli v\u011bt\u0161\u00ed \u0161anci \u017e\u00edt d\u00e9le plnohodnotn\u011bj\u0161\u00ed \u017eivot. V opa\u010dn\u00e9m p\u0159\u00edpad\u011b se zkracuje \u017eivot pacient\u016f a velk\u00e1 v\u011bt\u0161ina z nich m\u00e1 v\u00fdznamn\u011b omezenou pohyblivost a dal\u0161\u00ed komplikace.2\" \/>\n<meta property=\"og:url\" content=\"https:\/\/havas.cz\/pressroom\/prumerna-doba-diagnozy-bechterevovy-nemoci-je-devet-let-lide-si-ji-casto-pletou-s-beznou-bolesti-zad\/\" \/>\n<meta property=\"og:site_name\" content=\"Havas Prague\" \/>\n<meta property=\"article:modified_time\" content=\"2022-07-26T09:01:32+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/havas.cz\/pressroom\/prumerna-doba-diagnozy-bechterevovy-nemoci-je-devet-let-lide-si-ji-casto-pletou-s-beznou-bolesti-zad\/\",\"url\":\"https:\/\/havas.cz\/pressroom\/prumerna-doba-diagnozy-bechterevovy-nemoci-je-devet-let-lide-si-ji-casto-pletou-s-beznou-bolesti-zad\/\",\"name\":\"Pr\u016fm\u011brn\u00e1 doba diagn\u00f3zy Becht\u011brevovy nemoci je dev\u011bt let. 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